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Updated: Jul 2, 2025

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry
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DOT1L通过促进MYC/Mondo转录因子在染色质上的降解周期来刺激MYC/Mondo转录因子的活动

Gian P Sepulveda1,2, Ekaterina S Gushchanskaia1,3, Alexandra Mora-Martin1,4

  • 1Department of Biochemistry & Cell Biology, Boston University School of Medicine, Boston, MA, 02118, USA.

bioRxiv : the preprint server for biology
|February 19, 2024
PubMed
概括

这项研究揭示了DOT1L/DOT-1.1如何帮助从DNA中去除c-MYC/MML-1等转录因子,从而有可能提供新的癌症治疗策略.

关键词:
DOT-1.1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .DOT1LL 在线播放H3K7979 在线播放在MML-1中,它是MML-1.核蛋白质组的核蛋白质组是什么蛋白质溶解性裂变 蛋白质溶解性裂变转录 转录 转录 转录乌比奎丁-蛋白酶体系统这是一个VCPVCP.c-MYCC 这是一个很好的例子.

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