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Updated: Jul 2, 2025

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B细胞急性淋巴细胞白血病的克隆性进化 (del(9)(p13p21) 变成混合表型急性白血病,呈现为孤立的丸复发

Lane H Miller1,2, Sunita I Park3, Debra Saxe4

  • 1Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Emory University, Atlanta, GA 30322, USA.

Reports (MDPI)
|February 19, 2024
PubMed
概括

本案例研究详细介绍了一例罕见的混合表型急性白血病 (MPAL) 复发案例,该病例发生在最初被诊断为B细胞急性淋巴细胞白血病 (B-ALL) 的患者身上. 这种复发呈现为一种孤立的外骨髓性病变,突出显示了急性白血病中不寻常的克隆进化.

关键词:
B-ALL,所有的人.在MPAL中,MPAL是MPAL.克隆的进化过程德尔 (德尔) 在第九季 (p13p21)

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The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
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