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在上游生物处理中评估一次性光学和电化学pH传感器

Erica J Fratz-Berilla1, Casey Kohnhorst1, Nicholas Trunfio1

  • 1U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Pharmaceutical Quality, Office of Biotechnology Products, Division of Biotechnology Review and Research II, Silver Spring, MD, USA.

Heliyon
|February 19, 2024
PubMed
概括

单次使用的pH传感器在生物处理中提供了方便,但存在局限性. 光学传感器的精度低于电化学探针,特别是在pH值偏移时,影响工艺控制和产品质量.

关键词:
生物制造 生物制造 生物制造生物加工是一种生物加工.生物反应器 生物反应器查查查查查查查查查查查中国仓鼠的卵巢细胞.单克隆抗体是一种单克隆抗体.过程控制 过程控制一次性使用技术.控制pH值 控制pH值一个pH值传感器.

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