鼻恶性瘤治疗后的SNOT-22子域结果:一项前性多中心研究
David R Grimm1, Daniel M Beswick2, Sabrina L Maoz2
1Department of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto, California, USA.
International forum of allergy & rhinology
|February 19, 2024
概括
鼻恶性瘤 (SNM) 的治疗显著改善了生活质量 (QOL),特别是在鼻科,心理和睡眠领域. 然而,辅助化学辐射和pterygopalatine fossa的参与可能会对结果产生负面影响.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
- 生活质量研究 研究 生命质量研究
背景情况:
- 鼻腔恶性瘤 (SNM) 显著影响患者的生活质量 (QOL).
- 22项的鼻结局测试 (SNOT-22) 是评估鼻质量的一种验证措施.
- 之前的研究表明,在SNM治疗后,QOL有所改善.
研究的目的:
- 描述SNOT-22在SNM患者中的特定子域结果.
- 确定在SNM治疗期间和之后影响QOL变化的因素.
主要方法:
- 预期将SNM患者纳入多中心注册表.
- 在诊断时收集SNOT-22得分,并在治疗后长达5年.
- 多变量回归分析以确定SNOT-22子域结果的预测因素.
主要成果:
- 在治疗后的鼻科,心理和睡眠子域中观察到显著的改善 (p < 0.05).
- 辅助化学辐射与更糟糕的鼻腔,鼻外和耳朵/面部结果相关.
- 甲腔的干涉和积极的外科手术边缘与较差的鼻科,耳/面部和心理结果有关.
结论:
- 治疗SNM导致显著的QOL改善,主要是由于鼻腔,鼻外,心理和睡眠领域的改善.
- 特定的治疗方式 (例如,辅助化学辐射) 和疾病因素 (例如,pterygopalatine fossa参与) 可能会对QOL结果产生负面影响.
相关概念视频
Suctioning the Nasopharyngeal Airway
417
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
417
Tonsillitis II: Management
111
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
111
Chronic Pharyngitis
2.1K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
2.1K
Epistaxis
151
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
151


