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在大肠杆菌中皮表皮生长因子 (cEGF) 的表达调节了十二指肠的微生物群结构,以改善 brojlers 的生长性能和肠道形态发生

C Q Shan¹, Q C Liu², J Li²

¹School of Biological Engineering, Dalian Polytechnic University, Dalian, China.

British poultry science

|February 19, 2024

概括

皮表皮生长因子 (cEGF) 补充改善了 brojler 的生长性能和肠道健康. 这项研究证明了cEGF.

科学领域:

动物科学动物科学
生物技术是生物技术.
微生物学微生物学

背景情况:

抗生素增长促进剂在 brojiler养殖中被广泛使用,但引起了对抗生素耐药性的担忧.
需要采用替代策略来提高肉生长性能和肠道健康.

研究的目的:

调查皮表皮生长因子 (cEGF) 食补充对肉生长性能,肠道形态,消化酶活动和肠道微生物群的影响.
评估cEGF作为抗生素增长促进剂的潜在替代品.

主要方法:

用基因合成来获得cEGF的功能域,并构建了一个重组表达矢量.
一百八十只Arbor Acres肉被分为三个组:控制饮食 (ND),cEGF饮食 (250毫克/公斤) 和甲素饮食 (250毫克/公斤).
分析了生长性能,肠道形态,消化酶活动和十二指肠菌群.

主要成果:

饮食中使用cEGF补充剂降低了料转换率 (FCR) 和改善了平均每日料摄入量 (ADFI).
cEGF增加了十二指肠和阴道的高度,并增强了诸如α-氨酶和性酸酶等消化酶的活性.
补充cEGF改变了肠道微生物群的组成,增加了多样性指数 (ACE和Chao1) 并丰富了特定的细菌系.

结论:

饮食中的cEGF通过增强肠道发育和消化酶活性,有效地改善 brojler 的生长性能.
cEGF的积极作用可能与十二指肠微生物群的调节有关.
cEGF为促进 brojiler养殖增长提供了一个有希望的无抗生素替代品.

关键词:

brojler 肉肉是一个根据EGF的规定,EGF可以通过cEGF进行投资.十二指肠的微生物群酶活性的酶活动.增长的增长增长的增长增长的增长.小肠的形态小肠的形态.

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