一个强大的多营养物质动力模型,用于增强蛋白和生物质产量,用于混合性微藻种植:迈向成功的大规模生产的一步
Jihed Bentahar1,2, Jean-Sébastien Deschênes1,2
1Département de mathématiques, d'informatique et de génie, Collectif de recherche appliquée aux bioprocédés et à la chimie de l'environnement (CRABE), Université du Québec à Rimouski, Rimouski, Québec, Canada.
Biotechnology and bioengineering
|February 19, 2024
概括
微藻的混合养可以促进生物质和蛋白的生产. 一个新的运动模型准确地预测了各种营养条件下的生长,优化了大规模应用的产量.
科学领域:
- 生物技术是生物技术.
- 微藻养殖 微藻养殖
- 生物化学工程 生物化学工程
背景情况:
- 混合营养培养提高了微藻生物质和有价值化合物的生产率.
- 优化营养条件是最大限度地提高产量的关键.
- 对于过程控制和扩展,需要精确的运动模型.
研究的目的:
- 开发一种新的动力模型,用于混合培养Tetradesmus obliquus.
- 明确描述关键环境因素对生物质和黄蛋白生产的影响.
- 为大规模的微藻生产提供指导.
主要方法:
- 开发了一个带有7个状态变量和13个参数的动力模型.
- 进行了双因素,四级实验设计,用于校准和验证.
- 研究了涉及酸盐,酸盐和葡萄糖的多营养物质动力学.
主要成果:
- 模型准确地预测了生物质和黄蛋白的动态度概况.
- 优化的可用性使生物质增加了四倍,而蛋白增加了12倍.
- 达到6.80g/L的最大生物质和25.58mg/L的黄蛋白,增长速度为4.03天-1.1.
结论:
- 开发的动力模型对于混合营养培养具有广泛的适用性和准确性.
- 混合型种植提供了相对于光自otrophic 和异质型方法的协同效益.
- 结果为实时光生物反应器操作策略提供了基础.
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