图像吞功能和驱动食障碍的机制在包容体肌肉炎中
Sharfaraz Salam1, Jodi Allen2, Mazen M Dimachkie3
1Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology and The National Hospital for Neurology and Neurosurgery, London, UK.
Clinical and experimental rheumatology
|February 19, 2024
概括
偶发性包容体肌肉炎 (IBM) 导致吞问题,影响生活质量. 这篇评论探讨了成像技术,以了解和测量IBM患者的消化障碍.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
- 医疗成像医学成像
背景情况:
- 偶发性包容体肌炎 (IBM) 是一种进展性神经肌肉疾病,影响40岁以上的人.
- 吞障碍 (吞障碍) 影响高达80%的IBM患者,导致显著的发病率和并发症,如吸入性肺炎.
- 确切的病理生理学在IBM的消化不良,特别是口腔喉和口腔喉缺陷的作用,仍然不清楚.
研究的目的:
- 审查目前用于评估IBM患者吞功能的成像技术.
- 从成像研究中获得的,提供了对IBM的消化障碍机制的见解.
- 在IBM中建议未来的功能障碍评估和结果测量的方向.
主要方法:
- 审查现有的文学对成像模式的功能障碍的评估.
- 从成像研究 (例如,视频光学吞研究 - - VFSS) 获得的证据分析了IBM的口腔喉和口腔喉功能.
- 讨论当前方法的局限性,包括从VFSS辐射暴露.
主要成果:
- 图像证据表明,口腔大缺陷是IBM中缺食的主要驱动因素.
- 结构变化的精确贡献与肌肉损伤在cricopharyngeus还没有完全阐明.
- 目前的评估工具缺乏验证,对于IBM缺乏有效的失调治疗方法.
结论:
- 在IBM中食障碍是一个重要的临床挑战,需要更好地理解和管理.
- 先进或替代的成像技术具有潜力,可以作为IBM中吞的结果措施.
- 需要进一步的研究来开发验证的评估工具和针对性治疗干预措施,以治疗与IBM相关的食障碍.
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