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Updated: Jul 2, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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Published on: November 28, 2017

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利用交叉连接质谱来建模抗体-抗原复合体

Andrea Di Ianni1,2, Alessio Di Ianni3, Kyra Cowan4

  • 1NBE-DMPK Innovative BioAnalytics, Merck Serono RBM S.p.A., an Affiliate of Merck KGaA, Darmstadt, Germany, Via Ribes 1, Colleretto Giacosa (TO) 10010, Italy.

Journal of proteome research
|February 19, 2024
PubMed
概括

交联质谱法 (XL-MS) 有助于绘制抗体-抗原相互作用的地图. 这项研究证明了XL-MS数据.

关键词:
生物治疗药物 生物治疗药物交叉链接质谱仪的质谱仪.数据驱动整合建模数据驱动整合建模药物的发现和开发.表位/副位的映射绘制.

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