腹腔介质瘤中的静脉血栓栓塞:揭示隐藏的风险
Varun V Bansal1, Owen Mitchell2, Celyn Bregio3
1Division of Surgical Oncology, Yale School of Medicine, New Haven, CT, USA.
Annals of surgical oncology
|February 19, 2024
概括
腹膜间皮瘤 (PeM) 患者有高风险的静脉血栓塞栓症 (VTE). 标准的血栓预防似乎有效地减少术后静脉瘤发作事件.
科学领域:
- 在瘤学瘤学.
- 血管医学 血管医学
- 手术并发症 手术并发症
背景情况:
- 静脉血栓塞栓症 (VTE) 是已知的腹部癌症的并发症.
- 腹性间皮瘤 (PeM) 患者面临高静脉瘤风险,但具体特征尚未得到充分记录.
研究的目的:
- 调查腹膜间皮瘤患者中VTE的发病率和风险因素.
- 为了评估VTE和PeM患者的整体存活率之间的关联.
- 评估当前血栓预防方案的有效性.
主要方法:
- 对120名腹间皮瘤患者的回顾性分析.
- 评估VTE频率和后勤回归用于风险因素识别.
- 评估VTE与整体存活率和术后结果的相关性.
主要成果:
- 21.7%的PeM患者患有静脉瘤,主要是症状性肺栓塞.
- 在经过4周的血栓预防治疗后,术后静脉瘤发作率为4.4%.
- 在非手术患者中,低血清白蛋白是VTE的危险因素.
结论:
- 腹膜间皮质瘤患者在整个疾病过程中表现出高风险的VTE.
- 目前的4周血栓预防方案对于术后静脉瘤预防是有效的.
- 在PeM患者中,VTE没有显著影响整体存活率.
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