与银瓦纳达特相关的牙膏粘合剂:在烯酸树脂表面对多种生物膜的抗菌方法
D T de Castro1, I Ferreira2, V C Oliveira3
1Postdoctorate, Department of Dental Materials and Prosthodontics, Ribeirao Preto School of Dentistry, University of Sao Paulo, Ribeirao Preto- SP, Brazil.
The European journal of prosthodontics and restorative dentistry
|February 19, 2024
概括
添加到假牙粘合剂中的白银瓦纳酸纳米颗粒 (β-AgVO3) 显示出对常见的口腔病原体具有显著的抗微生物活性. 这项创新提供了一种有前途的策略,以提高假牙卫生,并预防与生物膜相关的感染.
科学领域:
- 材料科学 材料科学 材料科学
- 微生物学 微生物学
- 生物技术是生物技术.
背景情况:
- 假牙粘合剂易受微生物殖民,导致口腔健康问题.
- 开发抗微生物假牙粘合剂对于改善假牙卫生至关重要.
- 纳米材料为牙科材料中的抗微生物应用提供了新的解决方案.
研究的目的:
- 评估假牙粘合剂的抗菌潜力,这些粘合剂包含纳米结构的银瓦纳酸盐,并与银纳米颗粒 (β-AgVO3) 装饰.
- 评估β-AgVO3修饰粘合剂对多种口服生物膜的有效性.
- 为了比较奶油和粉末假牙粘合剂与β-AgVO3.3的抗菌性能.
主要方法:
- 烯酸树脂样本被处理为假牙粘合剂,其中含有不同度 (1%,2.5%,5%,10%) 的β-AgVO3.3.
- 对照组使用了没有β-AgVO3.3的超级科雷加奶油 (UCC) 和超级科雷加粉 (UCP).
- 使用每毫升殖民地形成单位 (CFU/mL),色度测试和光显微镜对抗Candida albicans,Candida glabrata,Streptococcus mutans和Staphylococcus aureus的抗菌活性进行了评估.
主要成果:
- 低度 (1%) 的β-AgVO3 完全抑制了 Streptococcus mutans 在两种粘合剂类型.
- 高度的β-AgVO3显著降低了代谢活性,并抑制了其他测试的微生物,除了Candida albicans的一些例外.
- 显微镜检测显示,在接受β-AgVO3治疗的组中,生物膜的形成减少,尽管与奶油相比,粉末粘合剂的整体生物膜形成较高.
结论:
- 用β-AgVO3配制的牙膏粘合剂对多种口腔生物膜具有显著的抗微生物特性.
- β-AgVO3 是一种有前途的添加剂,用于开发具有改善卫生性质的增强型假牙粘合剂.
- 进一步的研究可能会优化配方,以最大限度地提高抗菌疗效,并最大限度地减少生物膜粘附.
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