E-cadherin: TRAIL

Ser Hui San1, Siew Ching Ngai1

  • 1School of Biosciences, Faculty of Science and Engineering, University of Nottingham Malaysia, 43500 Semenyih, Selangor, Malaysia.

Gene
|February 19, 2024
PubMed
概括

重新表达的E-cadherin可以克服癌细胞对瘤亡因子 (TNF) 相关的亡诱导配体 (TRAIL) 治疗的抵抗力. 这一策略增强了TRAIL诱导的亡,并通过逆转上皮细胞到介质细胞转换 (EMT) 来防止癌细胞的入侵.

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