种族差异及其与心上脂肪组织厚度和心脏代谢参数之间的关联
Was Mohamed1,2, K N Ishak1, N Baharum3
1Nutrition, Metabolism and Cardiovascular Research Centre (NMCRC), Institute for Medical Research (IMR), National Institutes of Health (NIH), Ministry of Health (MOH), Shah Alam, Malaysia.
Adipocyte
|February 19, 2024
概括
在马来西亚,患有急性冠状动脉综合征 (ACS) 的马来西亚人中,心上脂肪组织 (EAT) 的厚度更大. EAT与代谢综合征成分有关,可能作为心血管风险标志物.
科学领域:
- 心脏病学 心脏病学
- 代谢综合征研究 代谢综合征研究
- 医疗成像医学成像
背景情况:
- 过多的上心脂肪组织 (EAT) 与心血管疾病 (CVD) 有关.
- 了解不同人群中的EAT对于评估心血管疾病风险至关重要.
研究的目的:
- 为了研究多民族马来西亚人的心上脂肪组织 (EAT) 厚度.
- 评估EAT厚度与代谢综合征组件之间的关联.
- 为了比较患有和没有急性冠状动脉综合征 (ACS) 的患者的EAT厚度.
主要方法:
- 使用标准的二维心声回声学来量化EAT厚度的非侵入性量化.
- 招募了213名有或没有ACS的马来西亚患者.
- 对影响EAT厚度的人口因素和并发症的分析.
主要成果:
- 与非ACS患者 (3.7毫米;p=0.035) 相比,ACS患者表现出明显更厚的EAT (4.1毫米).
- EAT的厚度与2型糖尿病 (T2DM) 和脂质失调有关.
- 中国族人表现出最厚的EAT分布 (4.6毫米).
- 在所有组中,年龄和透气血压与EAT厚度相关.
结论:
- 在马来西亚ACS患者中,EAT厚度显著更高.
- EAT受代谢综合征成分,人口统计和并发症的影响.
- 需要进一步的研究来确定EAT作为马来西亚ACS患者心血管风险标志物.
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