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相关概念视频

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Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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一项试点研究提出了一个算法,用于在脑中诱导青春期.

Anne Trinh1,2, Angelina Lim3,2, Phillip Wong4,2

  • 1Monash Health, Clayton, VIC, Australia.

Journal of pediatric endocrinology & metabolism : JPEM
|February 19, 2024
PubMed
概括
此摘要是机器生成的。

这项研究发现,性激素补充对治疗脑 (CP) 患者延迟青春期有益且耐受良好. 建议在严重的青春期延迟或停产时提前考虑激素治疗.

关键词:
大脑大脑大脑的大脑身体残疾就是残疾.激素 激素 激素 激素 激素催眠症是什么意思?催眠症是什么意思青春期的青春期,就是青春期.

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科学领域:

  • 儿科内分泌学 儿科内分泌学
  • 神经学 神经学
  • 生殖医学 生殖医学

背景情况:

  • 迟到的青春期是患有脑性麻 (CP) 的儿童的一个担忧.
  • 目前针对CP的青春期延迟的诊断和治疗方案需要进一步调查.
  • 性激素补充剂是延迟青春期的潜在干预措施.

研究的目的:

  • 调查脑 (CP) 患者中延迟青春期的患病率和特征.
  • 评估一种新的算法在CP中诱导青春期的可接受性和有效性.
  • 评估青春期诱导对骨健康的影响,不良影响,流动性和生活质量.

主要方法:

  • 这是一项两阶段的队列研究,涉及患有CP和延迟青春期的儿童和青少年.
  • 第一个阶段:对有关性类固醇治疗经验的临床记录和访谈进行回顾性审查.
  • 第二阶段:使用透皮 (男性) 或雌激素 (女性) 诱导青春期算法的前性试验,随访两年.

主要成果:

  • 在第一阶段的20名参与者中,有11名参与者能耐受性类固醇治疗.
  • 在第二阶段,10名参与者中有7人使用拟议的算法在9个月内达到坦纳的第三阶段.
  • 通过双能X射线吸收计 (DXA) 扫描的参与者中,高度调整的骨矿物质密度 (BMAD) Z-分数的平均变化为+0.27% (SD 0.002).

结论:

  • 迟到的青春期在CP中可能被诊断为晚期,突出需要及时查.
  • 建议的青春期诱导算法是可以接受的,并显示出有益的影响.
  • 对于所有患有严重的青春期延迟或CP停滞的患者,应考虑服用性激素补充剂,因为它的好处和耐受性.