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Updated: Jun 20, 2026

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
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在精密医学中对ex vivo样品处理的功能和分子影响的划分

Nona Struyf1, Albin Österroos2, Mattias Vesterlund3

  • 1Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden. nona.struyf@ki.se.

NPJ precision oncology
|February 19, 2024
PubMed
概括

样本处理显著影响急性髓性白血病 (AML) 研究. 生物银行改变了细胞表型和药物反应,影响了翻译研究的可复制性,需要仔细的标准化.

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相关概念视频

Fixation and Sectioning01:03

Fixation and Sectioning

Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens.
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...