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图像对比度,分辨率和阅读器专业知识对黑洞识别在多发性硬化症的影响
Mario Tranfa1, Alessandra Scaravilli1, Chiara Pastore1
1Department of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.
Neuroradiology
|February 20, 2024
概括
检测多发性硬化症 (MS) 黑洞 (BH) 是至关重要的. 一个3毫米重新切割的GRE-T1w序列提供可靠的BH检测,与标准SE-T1w相比,与更高分辨率的1毫米扫描不同.
科学领域:
- 神经辐射学神经辐射学
- 神经成像是一种神经成像.
- 多发性硬化症研究研究
背景情况:
- 多发性硬化 (MS) 病变中的黑洞 (BH) 是神经放射学评估中的关键指标.
- 不同的MRI序列用于BH评估,可能会影响诊断可靠性.
研究的目的:
- 评估不同MRI序列,分辨率和读者专业知识对识别MS黑洞 (BH) 的可靠性的影响.
主要方法:
- 使用3毫米的SE-T1w,1毫米的3D-GrE-T1w和重新切割的3毫米的3D-GrE-T1w序列进行85名MS患者的大脑MRI扫描的前性评估.
- 由两位不同专业知识的读者进行独立的图像分析,在30天的洗期后重复.
- 类内相关系数 (ICC) 用于确定读者内部和读者之间的可靠性.
主要成果:
- 对于3毫米的SE-T1w和3毫米重新切割的GRE-T1w序列,观察到优异的读取器内可靠性 (ICC ≥0.95).
- 对于1毫米的3D-GrE-T1w序列,发现了中度的读取器内可靠性 (ICC < 0.90).
- 这三个序列都显示了中度的读者间可靠性 (ICC < 0.90).
结论:
- 1毫米3D-GrE-T1w序列的高空间分辨率可能会增加BH检测中的读取器内部变异性.
- 建议使用3mm重切的GrE-T1w序列进行BH计数,以达到与标准3mmSE-T1w序列相当的可靠性.
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