草药足浴在糖尿病外围神经病变患者的效果和安全性:多中心双盲随机对照试验
Hao-Yue Huang1,2,3,4, Yu-Ping Lin1,2,3,4, Hua Wei1,2,3,4
1Department of Endocrinology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, 510120, China.
Chinese journal of integrative medicine
|February 20, 2024
概括
使用Tangbi Waixi (TW) 的足浴对于糖尿病外围神经病变 (DPN) 是安全的. 低剂量的TW在改善DPN症状和神经功能方面显示出比高剂量更大的好处.
科学领域:
- 传统中国医药 传统中国医药
- 神经学 神经学
- 药理学 药理学是指药理学的学科.
背景情况:
- 糖尿病外围神经病变 (DPN) 是糖尿病的常见并发症,导致显著的发病率.
- 目前对DPN的治疗方法的疗效有限,并且可能会产生副作用.
- 草药足浴代表了DPN管理的潜在补充疗法.
研究的目的:
- 为了调查唐比怀西 (TW) 足浴用于治疗DPN的疗效和安全性.
- 为了比较不同剂量的TW对DPN患者的影响.
主要方法:
- 一个多中心,双盲,随机对照试验,涉及632名DPN患者.
- 干预组每天接受TW足浴 (66.9克颗粒) 2周,然后休息2周,进行3次疗程.
- 对照组在相同的方案下接受了较低的剂量 (6.69克颗粒). 主要结果:多伦多临床评分系统 (TCSS-TS) 总分的变化. 二次结果:神经传导速度 (MNCV,SNCV).
主要成果:
- 与基线相比,高剂量和低剂量的TW显著改善了TCSS-TS得分和神经传导速度.
- 低剂量TW组在12周时表现出TCSS-TS的更大降低,在24周时表现出中枢神经SNCV的更显著增加.
- 两组之间没有观察到不良事件的显著差异,也没有发生与治疗相关的严重不良事件.
结论:
- TW足浴是一种安全有效的DPN治疗方法.
- 较低的TW剂量似乎比较高的剂量更有利于控制DPN症状和改善神经功能.
更多相关视频
05:06Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise
Published on: July 14, 2023
1.7K
08:15Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
Published on: May 10, 2024
570
相关概念视频
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
773
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
773
Peripheral Artery Disease IV: Nursing Management
714
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
714
Diabetic Foot Ulcer
45
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
45
Diabetic Neuropathy
99
DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
99
