儿科炎症性肠病中的疲劳:系统性审查和单一中心的经验
Shira T Turner1, Gili Focht2, Esther Orlanski-Meyer2
1Department of Psychology, Ben Gurion University of the Negev, Beersheba, Israel.
Journal of pediatric gastroenterology and nutrition
|February 20, 2024
概括
疲劳在儿科炎性肠病 (PIBD) 中很常见,影响大多数患有活跃疾病的儿童,甚至有一些在缓解期. 目前的测量工具有限,突出了对 PIBD 具体评估的需求.
科学领域:
- 胃肠病学 胃肠病学
- 儿科 儿科 儿科
- 炎症性肠道疾病研究研究
背景情况:
- 疲劳是儿科炎性肠病 (PIBD) 的重要且经常使人衰弱的症状.
- 现有的关于PIBD中疲劳的文献有限,缺乏特定的测量工具.
- 了解疲劳的流行和影响对于改善患者护理和生活质量至关重要.
研究的目的:
- 系统地审查有关儿科炎性肠病 (PIBD) 疲劳的现有文献.
- 探索目前用于测量这一群体疲劳的方法.
- 为了确定PIBD患者的初始队列中疲劳的近似率.
主要方法:
- 进行了系统的文献审查,确定了14项相关研究.
- 在预期的PIBD队列 (n=80) 和健康对照 (n=44) 中,使用IMPACT-III问卷中的两个特定问题来评估疲劳.
- 数据是在诊断后的4个月和12个月收集的,得分从0到100不等 (较低的得分表明更大的疲劳).
主要成果:
- 系统审查发现PIBD疲劳的研究有限,只有两个提供流行率,没有特定的PIBD测量工具.
- 在初始队列中,78%的儿童报告至少轻度疲劳 (得分≤75),33%报告中度疲劳 (得分≤50),11%报告严重疲劳 (得分≤25).
- 与健康对照组相比,PIBD患者 (9%中度疲劳) 的疲劳率明显高于健康对照组 (p=0.007),并且在活跃疾病 (92%) 和缓解 (63%,p=0.01) 中更高.
结论:
- 在PIBD中,文献稀缺,没有专门的测量工具来测量疲劳.
- 疲劳在患有PIBD的儿童中非常普遍,影响了绝大多数儿童,包括那些处于缓解状态的儿童.
- 需要进一步的研究来开发和验证PIBD特定的疲劳评估仪器.
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