在小儿科队列中同时患有乳病和性食道炎:不仅仅是一个巧合
Arielle Bergman1,2, Melanie Greifer1, Jeremiah Levine1
1Weill Cornell Medicine, Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, New York, NY, USA.
Clinical pediatrics
|February 20, 2024
概括
结核病 (CeD) 和性食道炎 (EoE) 经常同时存在. 患有CeD的患者患EoE的患病率高于预期,高色素细胞计数可以预测同时发生的EoE.
科学领域:
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
- 儿科 儿科 儿科
背景情况:
- 乳病 (CeD) 和性食道炎 (EoE) 是一种免疫媒介的胃肠道疾病.
- 这些情况可能会影响同一个患者,表明潜在的共享病理生理机制.
研究的目的:
- 确定患有CeD的儿科患者中EoE的患病率.
- 为了比较患有CeD和EoE患者的特征与仅患有CeD患者的特征.
主要方法:
- 在第三级护理医院进行的回顾性研究.
- 确定了148名患有CeD的儿科患者.
- 将同时出现CeD和EoE的患者与仅出现CeD的患者进行了比较.
主要成果:
- 在148名CeD患者中,11名 (7.4%) 也有EoE.
- 患有CeD和EoE的患者在诊断时具有显著更高的绝对乙素细胞计数 (454.1 ± 122.7对231.9 ± 19.4,P = .003).
结论:
- 在CeD患者中,EoE的患病率高于一般人群.
- 这表明CeD和EoE之间存在潜在的病理生理重叠.
- 周围绝对乙氨基酸细胞数量升高可能预测CeD患者同时发生的EoE.
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