在经过最小侵入性食道切除术后出现术后肺部并发症的外科风险因素
Xiaoxi Li1, Ling Yu1, Miao Fu1
1Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Anesthesiology, Peking University Cancer Hospital & Institute, Beijing, China.
International journal of general medicine
|February 20, 2024
概括
在微创食道切除术 (MIE) 后的术后肺部并发症 (PPC) 影响了25.2%的患者. 关键预测因素包括男性性别,BMI,COPD,新辅助化疗和放射治疗,低白蛋白和术后输血.
科学领域:
- 胸部外科手术 胸部外科手术
- 手术瘤学手术瘤学
- 肺部医学 肺部医学
背景情况:
- 手术后肺部并发症 (PPC) 是食道切除术后最常见的并发症.
- 在食道切除术后,PPC显著恶化了患者的预后.
- 最少侵入性食道切除术 (MIE) 的使用越来越多,需要了解其特定的并发症风险.
研究的目的:
- 为了确定与PPC相关的外科手术期间的风险因素,在McKeown MIE后.
- 开发一种预测模型,用于MIE患者的PPC.
主要方法:
- 对767名接受McKeown MIE (胸腔镜和腹腔镜) 的患者进行了回顾性分析.
- 评估患者特征,术后数据和术后并发症.
- 后勤回归分析以确定PPC的独立预测因素.
主要成果:
- 后性病的发生率为25.2% (193/767).
- 确定了独立的预测因素:男性性别,体重指数 (BMI) 升高,慢性阻塞性肺病 (COPD),新辅助化学放射治疗,术后低度的白蛋白和术后输血.
- 预测模型显示了中等准确度 (AUC = 0.671).
结论:
- 男性性别,BMI,COPD,新辅助化疗和放射治疗,术后的白蛋白水平和术后输血是MIE后PPC的显著独立预测因素.
- 这些发现可以为MIE患者的风险分层和有针对性的预防策略提供信息.
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