在COVID-19后,认知领域受到影响;系统性审查和元分析
Jack B Fanshawe1,2, Brendan F Sargent1,3, James B Badenoch4,5
1Department of Psychiatry, University of Oxford, Oxford, UK.
European journal of neurology
|February 20, 2024
概括
后COVID-19认知障碍影响多个大脑功能,包括执行功能和记忆力. 这一系统性审查强调了从COVID-19中恢复过来的个体中适度,广泛的认知缺陷.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 传染病研究 传染病研究
背景情况:
- COVID-19可能导致持续的神经认知后果.
- 了解认知障碍的模式对于康复至关重要.
研究的目的:
- 为了描述COVID-19后认知障碍的模式.
- 为临床管理和康复策略提供信息.
主要方法:
- 按照PRISMA-S指南进行系统审查和元分析.
- 包括评估认知领域>4周感染后的研究.
- 专注于高质量的研究 (>40名参与者,健康对照,低 attrition).
主要成果:
- 对执行功能,学习/记忆,复杂注意力和语言的损伤的适度效果大小.
- 感知运动功能表现出更大的损伤 (SMD -0.70).
- 在研究中没有发现任何特定的损伤模式.
结论:
- 在COVID-19后的多个领域中观察到一致的中度认知障碍.
- 研究中的异质性限制了解释性;表明大脑的广泛功能障碍.
- 未来的研究需要对神经和心理健康相互作用进行协调的测试和考虑.
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