儿童抑制控制能力的基于连接的神经标志物及其与人体质量指数的相关性
Jinfeng Han1, Kaixiang Zhuang2, Ximei Chen1
1Key Laboratory of Cognition and Personality, Ministry of Education, Faculty of Psychology, Southwest University, Chongqing, China.
概括
抑制性控制对健康成长至关重要,通过影响大脑连接,影响儿童的BMI. 这种控制的脑神经标志物可以预测未来的BMI,帮助预防儿童肥胖.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 维持正常的身体质量指数 (BMI) 对于儿童的健康发育至关重要.
- 儿童肥胖是一个日益关注的问题,需要对其潜在机制进行研究.
- 抑制性控制,一个关键的执行功能,被假设在调节BMI方面发挥作用.
研究的目的:
- 研究抑制控制与儿童的BMI之间的关系.
- 为了识别与抑制控制相关的大脑连接模式 (神经标记物).
- 探索抑制控制及其神经标志物如何影响儿童延迟满足和BMI之间的联系.
主要方法:
- 休息状态功能性MRI扫描被用来评估大脑连接.
- 使用基于连接的心理测量预测框架.
- 一组小学学生 (N=64,9-12岁) 参与了这项研究.
- 进行了为期一年的随访,以评估未来的BMI.
主要成果:
- 增强的抑制控制与执行功能大脑区域 (如上额叶) 的功能连接性增加相关.
- 抑制对照显示了与奖励相关的大脑区域 (例如轨道前叶) 的功能连接的负相关性.
- 抑制控制和其神经标志物都调节了与食物相关的延迟满足和BMI之间的联系;然而,只有神经标志物在一年后预测了未来的BMI.
结论:
- 这些发现揭示了通过抑制控制影响儿童BMI的神经通路.
- 抑制性控制的基于连接性的神经标志物显示出确定有肥胖风险的儿童的前景.
- 这项研究通过了解执行功能的作用,支持开发针对儿童肥胖的有针对性的干预措施.
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