胸部妄指数用于预测胸部手术后老年患者的术后妄:一个回顾性病例对照研究
Jianli Li1, Jing Liu1,2, Mingming Zhang1
1Department of Anesthesiology, Hebei General Hospital, Shijiazhuang City, China.
Brain and behavior
|February 20, 2024
概括
老年胸部手术患者的手术后妄 (POD) 可以使用新型指数预测. 这种胸部 Delirium Index (TDI) 包含年龄,血小板与白细胞比率 (PWR) 和疼痛评分,以准确评估风险.
科学领域:
- 老年医学 老年医学
- 胸部外科手术 胸部外科手术
- 神经科学是一个神经科学.
背景情况:
- 手术后痴呆症 (POD) 是经过胸部手术的老年患者的一个显著的神经并发症.
- POD可能导致严重的不良结果,需要有效的预测和管理策略.
研究的目的:
- 确定胸部手术后老年患者的POD风险因素,重点关注手术前血清生物标志物.
- 开发和验证一种新的胸部 Delirium 指数 (TDI),用于预测POD.
主要方法:
- 一项观察性研究包括279名年龄≥60岁的患者,接受了选择性胸部手术.
- 使用多变量回归分析确定了风险因素,包括血小板与白细胞比率 (PWR).
- 开发了一个TDI,并使用接收器操作特征 (ROC) 曲线分析评估了其对POD的预测准确性.
主要成果:
- POD的发病率为8.96% (在279名患者中25名).
- POD的独立风险因素包括年龄,PWR和前三个术后天内的平均疼痛得分.
- 对于POD,TDI显示了高的预测准确性 (曲线下的面积=0.790).
结论:
- 开发的胸部 Delirium Index (TDI) 有效地预测胸部手术后老年人的胸部 Delirium Index (TDI) 在胸部手术后有效预测老年人的胸部 Delirium Index (POD).
- 在这种患者群体中,TDI为管理POD风险提供了有价值的临床指导.
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