乌比基因特异蛋白酶1稳定PRRSV非结构蛋白Nsp1β,通过调节K48的乌比基因化,促进病毒复制

Yunyun Zhai1,2, Yongkun Du1,2, Hang Yuan3

  • 1College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, Henan, China.

Journal of virology
|February 20, 2024
PubMed
概括

猪生殖和呼吸系统综合征病毒 (PRRSV) 劫持宿主泛素特异蛋白酶1 (USP1) 以稳定其NSP1β蛋白,增强病毒复制. 抑制USP1提供了针对PRRSV感染的新策略.

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