初级甲状腺功能障碍和肉瘤:一个病例报告和文献综述
Burak Alper Zengin1, Adile Begüm Bahçecioğlu2, Murat Faik Erdoğan2
1Department of Internal Medicine, School of Medicine, Ankara University, Ibni Sina Hospital, Ankara, Turkey.
Journal of cancer research and therapeutics
|February 20, 2024
概括
原发性副甲状腺功能障碍症 (PHPT) 可能会增加骨肉瘤的风险,由于长时间暴露于副甲状腺激素. 建议早期干预和治疗,以减轻与PHPT相关的潜在风险.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 骨生物学 骨生物学
背景情况:
- 初级甲状腺功能障碍症 (PHPT) 和骨肉瘤之间的关联仍然存在争议,在teriparatide使用后,人们的担忧越来越大.
- 文献审查确定了10例PHPT与肉瘤和3例骨肉瘤的Teriparatide治疗后病例.
结论:
- 虽然大型队列没有显示增加的风险,但个别病例报告表明,长时间暴露在帕拉荷尔蒙和骨肉瘤之间存在潜在的关联.
- 预防PHPT患者长期暴露于帕拉荷尔蒙是一种谨慎的风险减轻方法.
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