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Updated: Jul 2, 2025

A Robust Single-Particle Cryo-Electron Microscopy cryo-EM Processing Workflow with cryoSPARC, RELION, and Scipion
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在eBIC的冷EM设施处理管道的基于服务的方法.

Anna Horstmann1, Stephen Riggs1, Yuriy Chaban2

  • 1Data Analysis, Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom.

Acta crystallographica. Section D, Structural biology
|February 20, 2024
PubMed
概括

本研究介绍了一种基于云的,面向服务的电子冷显微镜图像处理架构. 这种方法提高了高通量数据的实时处理效率,用于密度图学实验.

关键词:
云计算是云计算中的一个.化EM设备的设施.在eBICIC中,您可以使用eBIC.处理管道的加工管道.

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Cryo-electron Microscopy01:28

Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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