系统性关节炎:难以明确地命名一个连续的疾病
Gabriel Herrero-Beaumont1, Francisco Castro-Dominguez2, Alberto Migliore3
1Bone and Joint Research Unit, Rheumatology Dept, IIS-Fundación Jiménez Díaz UAM, Madrid, Spain. gherrero@fjd.es.
Aging clinical and experimental research
|February 20, 2024
概括
骨关节炎是一种复杂的系统性疾病,不仅仅是关节疼痛. 它涉及代谢问题,炎症,并影响整体健康,需要整体的治疗方法.
科学领域:
- 类风湿病学 类风湿病学
- 系统性疾病 系统性疾病
- 代谢健康 代谢健康
背景情况:
- 骨关节炎 (OA) 具有超出关节病理之外的全身影响.
- 致病机制包括代谢功能障碍,慢性炎症和神经因素.
- OA对生活质量,体力活动和心理健康产生负面影响.
研究的目的:
- 将骨关节炎 (OA) 重构为一个复杂的全身性疾病.
- 突出OA与代谢功能障碍,炎症和神经系统并发症的相互联系.
- 倡导一个整体和个性化的OA管理方法.
主要方法:
- 审查目前对关节炎病原学的理解.
- 分析OA作为一个复杂的系统与相互作用的组件.
- 检查肥胖和炎症在OA进展中的作用.
主要成果:
- 关节炎涉及诸如代谢功能障碍和慢性轻度炎症等全身性疾病.
- 肥胖是OA进展的关键驱动因素,需要控制.
- 骨髓炎会影响多个健康方面,包括精神健康和身体功能.
结论:
- 骨关节炎应该被视为一种全身性疾病,并加以管理.
- 整体和个性化的医疗护理对于有效的OA治疗至关重要.
- 将名称改为"系统性OA"可能会改善疾病的感知和管理.
更多相关视频
相关概念视频
Functional Classification of Joints
4.1K
Functional Classification of Joints
The functional classification of joints is determined by the amount of mobility between the adjacent bones. Joints are functionally classified as a synarthrosis or immobile joint, an amphiarthrosis or slightly moveable joint, or as a diarthrosis, a freely moveable joint. Fibrous and cartilaginous joints can be functionally classified as either synarthroses or amphiarthroses, whereas all synovial joints are classified as diarthroses.
Synarthrosis
An...
The functional classification of joints is determined by the amount of mobility between the adjacent bones. Joints are functionally classified as a synarthrosis or immobile joint, an amphiarthrosis or slightly moveable joint, or as a diarthrosis, a freely moveable joint. Fibrous and cartilaginous joints can be functionally classified as either synarthroses or amphiarthroses, whereas all synovial joints are classified as diarthroses.
Synarthrosis
An...
4.1K
Structural Classification of Joints
3.4K
Joints, also known as articulations, are classified based on their structural characteristics, i.e., based on whether the articulating surfaces of the adjacent bones are directly connected by fibrous connective tissue or cartilage, or whether the articulating surfaces contact each other within a fluid-filled joint cavity. These differences serve to divide the joints of the body into three structural classifications.
A fibrous joint is where the adjacent bones are united by fibrous connective...
A fibrous joint is where the adjacent bones are united by fibrous connective...
3.4K
Knee Joint
1.8K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
1.8K
Classification of Bones
5.5K
The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
5.5K
Overview of Systemic Arteries
812
The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
812
Structural Joints: Synovial Joints
3.5K
Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
3.5K


