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在健康经济评估中建模依赖参数的简化方法:一个教程

Xuanqian Xie1, Alexis K Schaink2, Sichen Liu3

  • 1Health Technology Assessment Program, Ontario Health, 525 University Avenue, 5th Floor, Toronto, ON, M5G 2L3, Canada. shawn.xie@ontariohealth.ca.

Applied health economics and health policy
|February 20, 2024
PubMed
概括

本教程简化了在健康经济模型中处理依赖参数的方法. 它介绍了模拟多变量正常数据和估计过渡概率的可访问方法,有助于复杂模型的开发.

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Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
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