人类乳头瘤病毒感染和疾病的危险因素:针对性的文献摘要
Marta Del Pino1, Alex Vorsters2, Elmar A Joura3
1Department of Obstetrics and Gynecology, Hospital Clínic of Barcelona, University of Barcelona, Barcelona, Spain.
Journal of medical virology
|February 20, 2024
概括
成年人可以从人类乳头瘤病毒 (HPV) 疫苗接种中受益. 成年人感染HPV的主要危险因素包括艾滋病毒阳性,多个性伴侣和吸烟,为有针对性的疫苗接种策略提供信息.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 青少年是常规人类乳头瘤病毒 (HPV) 疫苗接种的主要接收者.
- 未接种疫苗的成年人代表了HPV预防的错失机会.
- 缺乏对目标人群的共识和报销问题等障碍阻碍了成人HPV疫苗接种.
研究的目的:
- 审查和综合现有关于成人HPV感染和疾病风险因素的文献.
- 确定可以为成年人HPV疫苗接种策略的决策提供信息的因素.
- 支持高风险成年人群体HPV预防的政策和临床指南.
主要方法:
- 2009年至2020年间发表的153项研究的系统审查.
- 对成人HPV感染或疾病相关因素的相对风险或几率比率的分析.
- 综合发现,尽管研究设计和报告不一致.
主要成果:
- 证实了成年人HPV感染的几个显著风险因素.
- 确定人类免疫缺陷病毒 (HIV) 阳性作为一个关键的风险因素.
- 强调性伴侣的数量和吸烟是HPV风险的重要贡献者.
结论:
- 了解成人风险因素对于针对性HPV疫苗接种至关重要.
- 结果可以为公共卫生政策,临床指导方针和查方案提供信息.
- 解决疫苗接种障碍和准高风险群体可以改善成人HPV预防.
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