没有血中酒精度与烧伤患者结局的关联
Justin Bria1, Awni Shahait2, Luz Nagle1
1The Michael and Marian Ilitch Department of Surgery, Wayne State University School of Medicine, Detroit, Michigan.
The Journal of surgical research
|February 20, 2024
概括
烧伤患者血中酒精含量 (BAC) 较高与机械呼吸机使用时间较长相关,但不增加死亡率或并发症. 这项研究分析了酒精饮料.
科学领域:
- 创伤外科 手术 创伤外科
- 烧伤护理 烧伤护理
- 毒理学 毒理学 毒理学
背景情况:
- 在烧伤患者群体中,滥用酒精很普遍.
- 烧伤患者的酒精中毒与不良结果有关,包括器官衰竭和延长住院时间.
研究的目的:
- 为了研究血中酒精含量 (BAC) 水平与患者在烧伤损伤中的结果之间的关联.
- 为了确定较高的酒精含量是否会影响死亡率,发病率或在烧伤护理中的资源利用.
主要方法:
- 对2016年至2021年期间入院的197名烧伤患者的回顾性分析.
- 患者分为低 (<80 mg/dL) 和高 (≥80 mg/dL) 血中酒精含量 (BAC) 组.
- 使用单变量分析,比较两个BAC组之间的人口统计数据,并发症和临床结果.
主要成果:
- 高BAC组的机械呼吸器日数显著长 (16.7天与7.5天,P=0.026).
- 在死亡率 (9.3%对6.6%),整体发病率 (23.8%对16.0%) 或烧伤重症监护室 (ICU) 入院率方面,没有观察到群体之间的显著差异.
- 低BAC组显示了较高的第三度烧伤百分比 (15.4%对5.0%,P=0.024).
结论:
- 烧伤患者血中酒精含量升高与长时间的机械通风有关.
- 较高的BAC水平与增加的住院死亡率,整体住院时间或并发症率无关.
- 进一步的研究可能会探索针对需要机械支持的酒精相关烧伤患者的具体干预措施.
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