一种经过修改的天然小分子通过与Tubb3相互作用来抑制三阴性乳腺癌的生长

Hongwei Han1, Minkai Yang1, Zhongling Wen1

  • 1State Key Laboratory of Pharmaceutical Biotechnology, Institute of Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, 210023, China; Co-Innovation Center for Sustainable Forestry in Southern China, MOE Key Laboratory of Forest Genetics and Biotechnology, Nanjing Forestry University, Nanjing, 210037, China.

概括

一种新型的什科宁衍生物PMMB276有效向三阴性乳腺癌 (TNBC) 的β-图林同型III (Tubb3). 这种Tubb3抑制剂抑制瘤生长,为TNBC治疗提供了一个有前途的新治疗途径.

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