历史学不可知论:微分子化疾病?
Jonah Campbell1, Alberto Cambrosio1, Mark Basik2
1Department of Social Studies of Medicine, McGill University, Montreal, QC, Canada.
Studies in history and philosophy of science
|February 20, 2024
概括
低分子概念在癌症治疗中提炼了"分子化". 瘤学研究中的组织学不可知论重新配置药物开发和治疗,显示组织学不可知论.
科学领域:
- 科学与技术研究 研究科学与技术研究
- 在瘤学瘤学.
- 基因组学就是基因组学.
背景情况:
- "分子化"的概念描述了人体从解剖视图转向微观视图的转变.
- 健康和疾病越来越多地是由个人的遗传构成来定义的.
- 这种转变在 (后) 基因组瘤学中尤为重要.
研究的目的:
- 在 (后) 基因组瘤学中引入和探索"内分子"的概念.
- 分析如何在癌症研究和护理中的"组织学-不可知论"方法中实行下分子性.
- 检查这种方法对药物开发,临床试验,治疗决策和监管的影响.
主要方法:
- 基于北美瘤学环境中进行的现场研究.
- 分析"历史学不可知论"如何在癌症研究和临床护理中重新配置知识和实践.
- 检查下分子凝视的实际实施情况.
主要成果:
- 瘤学研究中的组织学不可知论在药物开发,临床试验和治疗决策方面部分重新配置了知识和实践.
- 下分子凝视涉及组织学作为组织学不可知药物的调节器的"回归".
- 基因组学为解释突变的复杂性提供了一个背景.
结论:
- 下分子概念在 (后) 基因组瘤学中提供了分子化的细微延伸.
- 基因组学不可知论,虽然似乎减少了基因组学的作用,但实际上重新引入它来解释复杂的基因组数据和指导治疗.
- 这一正在进行的修订影响了对癌症生物病理学和时间性的理解.
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