[对4名患有密码性组织性肺炎的儿童进行临床分析]
C Y Liu1, Y M Bao1, Y J Zheng1
1Department of Respiratory Disease, Shenzhen Children's Hospital, Shenzhen 518038, China.
Zhonghua er ke za zhi = Chinese journal of pediatrics
|February 20, 2024
概括
儿童的密码性组织性肺炎 (COP) 与咳和胸部CT发现类似于地面玻璃的不透明度. 葡萄糖皮质激素治疗对于治疗这种儿科肺部疾病是有效的.
科学领域:
- 儿科肺病学 儿科肺病学
- 呼吸系统医学 呼吸系统医学
- 病理学 病理学 病理学
背景情况:
- 密码性组织性肺炎 (COP) 是一种罕见的肺部疾病.
- 了解它在儿童中的临床特征对于及时诊断和管理至关重要.
研究的目的:
- 分析诊断COP的儿科患者的临床特征,成像发现,病理学,治疗和结果.
- 为儿童提供关于COP的介绍和管理的见解.
主要方法:
- 从4名病理确认COP的儿科患者的临床数据的回顾性分析.
- 数据包括临床表现,高分辨率计算机断层扫描 (HRCT) 发现,胸腔镜肺活检结果,治疗和患者结果.
- 患者于2004年1月至2022年12月期间在深儿童医院接受治疗.
主要成果:
- 所有4名患者都是男性,年龄为1岁3个月至14岁,诊断时间从3个月到3年不等.
- 常见的症状包括咳 (4/4),短呼吸 (2/4),喘息 (2/4),胸痛 (1/4).
- 在HRCT中显示了分散的双边地面玻璃不透明度,巩固和不齐的透. 胸腔镜肺活检证实了诊断,3名患者对葡萄糖皮质激素治疗反应良好,其中1名患者出现自发缓解.
结论:
- 儿科COP通常表现为咳,吐和胸痛,在较小的儿童中伴有短呼吸和喘息.
- 扩散的双边地面玻璃不透明度和整合是常见的CT发现.
- 病理学检查对于诊断至关重要,而葡萄糖皮质激素治疗显示出良好的疗效.
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