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Updated: Jul 2, 2025

Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells
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Published on: May 1, 2020

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miR-483-5p通过促进酸化Ser209eIF4E和4E-BP1水平的下降来协调蛋白质合成的启动.

Siranjeevi Nagaraj1,2, Anna Stankiewicz-Drogon3, Edward Darzynkiewicz1,3

  • 1Interdisciplinary Laboratory of Molecular Biology and Biophysics, Centre of New Technologies, University of Warsaw, 02-097, Warsaw, Poland.

Scientific reports
|February 20, 2024
PubMed
概括

微RNA-483-5p准了参与蛋白质合成的多种蛋白质,降低了化真核细胞启动因子4E (pSer209eIF4E) 的水平. 这种多目标能力为癌症等疾病提供了潜在的治疗策略.

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