高强度间歇训练与在主动监测下针对局部性前列腺癌的中等强度持续训练:系统性审查和网络元分析
Qiyu Zhu1, Xingyu Xiong1, Qian Zheng2
1Department of Urology, Institute of Urology, West China Hospital of Sichuan University, No. 37, Guoxue Alley, Chengdu, Sichuan, PR China.
Prostate cancer and prostatic diseases
|February 21, 2024
概括
高强度间歇训练 (HIIT) 和中等强度持续训练 (MICT) 都有利于局部前列腺癌患者的心肺健康. 在降低PSA水平方面,HIIT更有效,而MICT提供了更大的心肺呼吸系统改善.
科学领域:
- 运动生理学 运动生理学
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 局部性前列腺癌 (PCa) 的管理通常涉及到积极监测 (AS).
- 高强度间歇训练 (HIIT) 和中等强度持续训练 (MICT) 越来越多地用于AS的PCa患者.
- 对心肺健康和疾病进展的最佳运动方式尚不清楚.
研究的目的:
- 为了比较HIIT和MICT对心肺呼吸能力和生化进展的影响,在局部PCa患者中进行AS.
- 确定在主动监测期间管理PCa的最有利的练习模式.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析来源于PubMed,Cochrane和Embase.
- 包括用英语撰写的研究,遵守PRISMA指南.
- 主要结局:血清前列腺特异性抗原 (PSA) 和峰值VO2. 二级结局:PSA翻倍时间 (PSADT) 和. 使用Cochrane工具评估偏差风险.
主要成果:
- 分析了涉及222名患者的6个RCT.
- 与常规护理和MICT相比,HIIT显著降低了PSA水平.
- 与常规护理相比,HIIT和MICT都改善了VO2峰值,MICT显示出更好的心肺呼吸系统益处 (SUCRA 98.1%).
- HIIT显示PSA降低功效的概率最高 (SUCRA 97.8%). 没有发现PSADT或丸激素的显著差异.
结论:
- 无论是HIIT还是MICT,都为局部PCa患者提供了显著的心肺呼吸系统益处.
- 对于生物化学进展控制 (血清PSA降低) ,HIIT更有效.
- 在提高心肺呼吸能力方面,MICT是卓越的.
- 研究结果支持针对AS的PCa患者量身定制的运动干预措施.
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