倾向性得分权重与共变量和集群数据结构缺失的数据
1Department of Educational Psychology, The University of Texas at Austin.
Multivariate behavioral research
|February 21, 2024
概括
可以改进带有缺失和聚类数据的倾向性得分 (PS) 分析. 多层次归算和固定的效果PS模型减少偏差在治疗效果估计.
科学领域:
- 行为科学 行为科学
- 生物统计学 生物统计学
- 流行病学 流行病学
背景情况:
- 倾向性得分 (PS) 分析在行为科学中至关重要.
- 缺少共变量数据和集群数据结构使PS分析复杂化.
- 以前的研究已经分别解决了这些问题,而不是同时解决.
研究的目的:
- 评估使用缺失数据和集群数据进行PS权重分析的方法.
- 比较不同的缺失数据处理和PS权重策略.
- 确定复杂的PS分析场景的最佳方法.
主要方法:
- 进行了模拟研究,评估了各种缺失数据方法 (完整案例,单级归算,多级归算).
- 评估了不同的多层PS权重方法 (固定或随机效应的PS模型,反向倾向权重,集群权重).
- 检查了加权的单级或多级结果模型.
主要成果:
- 多级归算有效地处理了在集群设置中缺失的数据.
- 固定效应的PS模型,集群权重和加权的多层次结果模型减少了偏差.
- 结合适当的缺失数据处理和PS权重策略至关重要.
结论:
- 在缺失的数据处理 (多层次归算) 和PS分析 (固定效果PS模型,集群权重) 中对集群的计算将偏差降到最低.
- 这些发现为复杂的观察性研究提供了实际指导.
- 一个真实数据示例说明了推的方法.
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