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生存的孕产妇败血症:临床,实验室和治疗特征
Carolina C Ribeiro-do-Valle1, Adriana G Luz1, Rodolfo C Pacagnella1
1Department of Obstetrics and Gynecology, University of Campinas, (UNICAMP), Campinas, São Paulo, Brazil.
概括
孕妇的母性败血症很少是由耐药细菌引起的,广泛使用的是Access和Watch抗生素. 有效的机构政策和医疗保健专业人员的意识是最佳孕产妇败血症治疗和结果的关键.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 孕产妇的败血症对孕妇和产后妇女构成重大风险.
- 了解临床,实验室和治疗特征对于改善结果至关重要.
- 现有的败血症协议旨在标准化对这一脆弱群体的护理.
研究的目的:
- 确定怀孕或最近怀孕的孕妇被诊断患有孕产妇败血症的临床,实验室和抗生素治疗模式.
- 分析败血症的严重程度,并确定常见的致病原体及其耐药性概况.
- 根据AWaRe分类来评估抗生素的使用情况.
主要方法:
- 在巴西一家三级医院进行了一项回顾性队列研究 (2014年3月至2018年2月).
- 包括365名怀孕或最近怀孕的怀疑败血症的妇女 (不包括未经证实的感染).
- 收集了临床,实验室和管理特征的数据,并将其与败血症严重程度组 (败血症,严重败血症,败血性休克) 进行了比较.
主要成果:
- 与怀孕相关的和呼吸道感染是主要原因;尿路感染是败血性休克的主要原因.
- 几乎所有病例都采集了血液培养,总体阳性为10.8%,败血性休克患者为41%.
- 大肠杆菌 (Escherichia coli) 是最常见的病原体,对第三代类菌素的耐药性较低. 主要使用的是Access和Watch抗生素,没有发生产妇死亡.
结论:
- 在这个队列中,母亲的败血症很少与抗菌素耐药性有关.
- 接入组抗生素的广泛使用是可行的和有效的.
- 提高医疗保健专业人员的认识和强有力的机构政策对于有效管理孕产妇败血症和改善患者治疗结果至关重要.
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