在艾滋病毒感染者和未感染者中,偏好长效注射性ART和PrEP:阿根廷的一项横截面研究
Sergio Sciannameo1, Virginia Zalazar2, Luciana Spadaccini1
1Research Department, Fundación Huésped, Buenos Aires, Argentina.
Therapeutic advances in infectious disease
|February 21, 2024
概括
拉丁美洲的艾滋病毒感染者更喜欢长效注射抗逆转录病毒疗法 (ART). 同样,没有艾滋病毒的人更喜欢长效注射性暴露前预防 (PrEP),这表明需要多种艾滋病毒治疗和预防选择.
科学领域:
- 艾滋病毒/艾滋病研究研究
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 在拉丁美洲对抗逆转录病毒治疗 (ART) 和暴露前预防 (PrEP) 给药方法的偏好了解有限.
- 探索每日口服药丸与长效注射药 (LAI) 两种选择的治疗和预防.
研究的目的:
- 评估艾滋病毒感染者对ART的偏好.
- 评估在没有艾滋病毒的人群中对PrEP的偏好.
- 检查这些偏好的相关性和潜在原因.
主要方法:
- 从2021年4月到7月,进行了基于网络的横截面问卷调查.
- 一个艾滋病毒非政府组织的社交媒体平台被用于招聘.
- 该研究包括阿根廷的成年人,收集有关物质使用,心理健康,慢性疾病,先前注射药物使用经验和艾滋病毒状况的数据.
主要成果:
- 在1676名受访者中,91.5%的艾滋病毒感染者更喜欢长效注射性ART (LAI-ART).
- 对于LAI-ART的偏好在受教育程度较高的个人, cisgender 同性恋,双性恋和奇异男性,年轻的参与者以及具有先前注射经验的人中更高.
- 在没有艾滋病毒的人群中,68%的人更喜欢长效注射PrEP (LAI-PrEP),这与之前使用注射剂的积极经验有关.
结论:
- 对LAI-ART的强烈偏好表明,艾滋病毒感染者可能会改善坚持和福祉.
- 对LAI-PrEP的偏好强调了它在没有艾滋病毒的人群的艾滋病毒预防策略中的重要性.
- 这些发现强调了提供多样化的ART和预防方法的必要性,以提高拉丁美洲的医疗保健成果.
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