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Updated: Jul 2, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

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冠状动脉心脏病的多祖先多基因风险评分,基于一个祖先多样化的全基因组协会研究和特定人群优化

Johanna L Smith1, Catherine Tcheandjieu2,3,4, Ozan Dikilitas1

  • 1Department of Cardiovascular Medicine (J.L.S., O.D., I.J.K.), Mayo Clinic, Rochester, MN.

Circulation. Genomic and precision medicine
|February 21, 2024
PubMed
概括

冠心病 (CHD) 的多祖先多基因风险评分 (PRS) 在不同人群中显示出更好的表现. 需要对更大,代表性不足的数据集进行进一步的研究,以提高所有祖先的PRS准确性.

关键词:
冠状动脉疾病是一种冠状动脉疾病.遗传关联研究 遗传关联研究对疾病的遗传倾向.遗传风险评分 遗传风险评分遗传变异是一种遗传变异.赔率比率 赔率比率 的比率.

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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

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