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Updated: Jul 2, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
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Published on: February 3, 2023

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稳定突变的逐步引入揭示了 de novo TIM 桶中的非线性添加效应

Johanna-Sophie Koch1, Sergio Romero-Romero1, Birte Höcker1

  • 1Department of Biochemistry, University of Bayreuth, Bayreuth, Germany.

Protein science : a publication of the Protein Society
|February 21, 2024
PubMed
概括

设计像TIM桶这样的新型蛋白质需要了解突变如何影响稳定性. 这项研究表明,稳定突变的数量和位置都显著改变了蛋白质的稳定性,并观察到非添加效应.

关键词:
(β/α) 8个桶的现在我们要去除TIMs.在TIM的桶里,TIM的桶里.添加的效应是附加效应.不对称的不对称性一个新的蛋白质设计.蛋白质折叠 蛋白质的折叠

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