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母胎液中的微塑料及其与妊娠年龄的关联

Jiyang Xue¹, Zhendong Xu², Xiaobing Hu²

¹Department of Pharmacy, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200092, China.

The Science of the total environment

|February 21, 2024

概括

在羊水中发现的微塑料与降低妊娠年龄有关. 母亲的饮食,包括海鲜和瓶装水,可能会增加微塑料的暴露,对胎儿发育构成风险.

科学领域:

环境健康环境健康
生殖生物学生殖生物学
毒理学毒理学毒理学

背景情况:

微塑料 (MP) 污染是一个日益严重的全球性问题,对人类健康,尤其是胎儿健康构成潜在威胁.
关于胎儿MP暴露的来源及其对发育的影响的研究有限.
对羊水中的MP进行调查对于了解母胎转移和健康影响至关重要.

研究的目的:

确定MPs在人类羊水中的存在和特征.
探索母亲的饮食习惯和AF MP水平之间的关联.
评估AF MP丰度和胎儿生长指标之间的关系.

主要方法:

使用激光直接红外光谱 (LD-IR) 分析了40个人类AF样本.
关于MP聚合物类型,大小和形态的特征.
基于问卷的评估母亲的饮食习惯 (海鲜消费,瓶装水的摄入量).

主要成果:

在40个AF样本中32个检测到MPs (80%),平均丰度为2.01±4.19颗/g.
聚乙烯 (38.80%) 和化聚乙烯 (26.98%) 是最常见的聚合物;碎片 (71.23%) 主导.
AF MP水平与海鲜消费和瓶装水摄入量正相关.
在AF中较高的MP丰度与较低的妊娠年龄显著相关 (β = -0.44).

结论:

这项研究证实了MPs在人胎液中的存在.
母亲的饮食,特别是海鲜和瓶装水,可能是MP暴露的重要来源.
在AF中MP的存在与降低妊娠年龄有关,突出了对胎儿发育的潜在风险.
需要对MP传播机制和长期胎儿健康影响进行进一步的研究.

关键词:

通过饮食的暴露.胎儿的发育胎儿的发育人类的胎液是人类的胎液.微塑料是一种微塑料.怀孕怀孕怀孕怀孕

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