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Updated: Jul 2, 2025

Cell Death Associated with Abnormal Mitosis Observed by Confocal Imaging in Live Cancer Cells
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可光激活的,针对线粒体的dppz (III) 复合物选择性地相互作用并损害癌细胞中的线粒体DNA

Jana Kasparkova1, Vojtech Novohradsky2, José Ruiz3

  • 1Department of Biophysics, Faculty of Science, Palacky University, CZ-783 71, Olomouc, Czech Republic.

Chemico-biological interactions
|February 21, 2024
PubMed
概括

这项研究表明,循环金属化III复合物 (Ir1) 向癌细胞线粒体,结合并破坏线粒体DNA (mtDNA). 蓝光通过促进DNA裂变来增强其抗癌作用,这表明了一种新的光疗策略.

关键词:
它具有抗瘤活性.在DNA裂变的过程中,线粒体DNA是线粒体的DNA.光毒性复合物 复合物 复合物超氧化离子基是超氧化离子基.线粒体编码的基因的转录.

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