预后营养指数和脊柱手术后术后并发症的风险:一个元分析
Hubing Guo1, Lingxia Yang2, Jin Liu1
1The First Department of Orthopaedic Surgery, The First Hospital of Tianshui, Tianshui, P.R. China.
World neurosurgery
|February 21, 2024
概括
手术前预后营养指数 (PNI) 较低表明营养不良,并且与脊柱手术患者的术后并发症 (包括妄想和感染) 有关. 这一发现凸显了PNI作为脊柱手术后不良结果的关键风险因素.
科学领域:
- 外科手术的结果
- 营养科学 营养科学
- 临床流行病学临床流行病学
背景情况:
- 营养不良,以低预后营养指数 (PNI) 表示,与各种疾病的预后不佳有关.
- 预后营养指数 (PNI) 是一个随时可用的标记,反映了营养状况.
- 评估术前营养状况对于预测术后结果至关重要.
研究的目的:
- 系统地审查和元分析术前PNI与术后并发症风险之间的关联.
- 为了评估低PNI在脊椎手术后不良事件的预测值.
- 量化特定并发症的风险,如妄和手术部位感染,与手术前的PNI相关.
主要方法:
- 在PubMed,Embase和Web of Science进行了全面的文献搜索.
- 包括相关的队列研究,调查脊椎手术患者的手术前PNI和手术后并发症.
- 使用随机效应模型来合成数据,并考虑异质性.
主要成果:
- 十项包括3,249名患者的队列研究被纳入了分析.
- 低的手术前PNI与整体术后并发症的风险增加显著相关 (OR:1.82,95%CI:1.42至2.34).
- 较低的PNI与更高的术后妄风险相关 (OR: 2.36,95% CI: 1.52至3.66) 和手术部位感染 (OR: 1.41,95% CI: 1.15至1.73).
结论:
- 手术前的低预后营养指数 (PNI) 是脊椎手术后不良结果的重要风险因素.
- 低PNI与整体术后并发症,妄想和手术部位感染的发病率增加有关.
- 这些发现强调了在接受脊柱手术的患者中评估PNI的重要性,以确定那些风险较高的人.
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