使用行为科学来增加核心结果在试验中的使用.
Karen Matvienko-Sikar1, Shannen Hussey1, Katie Mellor2
1School of Public Health, University College Cork, Cork, Ireland.
Journal of clinical epidemiology
|February 21, 2024
概括
这项研究确定了行为策略,以增加在临床试验中使用核心结果集 (COS) 的使用. 这些策略包括教育,培训和说服,以改善研究标准化和减少浪费.
科学领域:
- 临床试验方法论的方法论.
- 在研究中的行为科学.
背景情况:
- 核心结果集 (COS) 增强临床试验标准化,减少结果异质性.
- 采用COS是一种可以通过有针对性的干预来影响的行为.
研究的目的:
- 确定可以增加在临床试验中使用COS的行为干预组件.
- 应用行为变化轮框架来理解和影响COS采用.
主要方法:
- 利用行为变化轮框架和COM-B模型来分析COS使用的障碍和促进因素.
- 两位审稿人从四项关于COS使用的研究中提取和编码了数据.
- 干预功能和行为改变技术 (BCT) 被确定和映射出来.
主要成果:
- 在COM-B模型的能力,机会和动机领域中确定了障碍物和促进者.
- 确定了五个干预功能和15个BCT,并开发了36个有形例子.
- BCT的例子包括提供有关COS福利和选择指南的信息,按交付方法分类.
结论:
- 该研究提供了各种行为干预组件,以促进在临床试验中使用COS.
- 需要进一步的研究来评估这些已识别的组件的有效性.
- 成功实施COS可以改善成果报告和减少研究浪费.
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