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发达的原发性闭角玻璃眼与白内障的phacogoniotomy与phacotrabeculectomy:一个随机的非劣势试验

Yunhe Song¹, Fengbin Lin¹, Aiguo Lv²

¹State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou 510060, China.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

|February 21, 2024

概括

角切除术在先进的初级闭角玻璃瘤 (PACG) 和白内障中降低眼内压力方面与角切除术同样有效. 这种新手术提供了更短的手术时间,更少的并发症和更好的生活质量.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
白内障手术手术白内障手术

背景情况:

与白内障相关的先进初级闭角光眼 (PACG) 对眼内压力 (IOP) 管理提出了重大挑战.
瘤切除术是一种常见的外科手术方法,但正在探索替代的最小侵入性选择.

研究的目的:

为了比较发达的PACG和同时存在的白内障的患者的法哥尼切除术与法哥尼切除术的有效性和安全性.
评估IOP减少,手术成功率,并发症概况和生活质量结果.

主要方法:

一个多中心,随机控制的非劣势性试验,涉及124名患有高级PACG和白内障的患者.
患者被分配到形形切除术 (65只眼睛) 或形形切除术 (59只眼睛) 中,并被跟踪12个月.
主要结局:与基线相比IOP降低;次要结局:手术成功,并发症,药物使用和生活质量 (EQ-5D-5L).

主要成果:

在IOP降低方面,法哥尼切除术证明与法科特拉贝克切除术无劣 (平均降低-26.1 mmHg vs. -25.7 mmHg).
这两种手术都显著减少了药物需求 (P < 0.001),成功率相似 (P = 0.890).
发管切除显示出更低的并发症率 (12.3%与23.7%相比),更短的手术时间 (22.1分钟与38.8分钟相比),以及更好的生活质量改善 (P = 0.010).

结论:

发管切除术是发管切除术的安全有效替代方案,用于治疗晚期的PACG和白内障.
该程序提供了优势,包括减少手术时间,减少并发症,提高患者的生活质量.

关键词:

白内障是什么?白内障是什么?白内障是什么?最少侵入性的玻璃眼外科手术.这是一种法科特拉贝克细胞切除术 (phacotrabeculectomy).主要关闭角度的玻璃眼 (Glaucoma)随机对照试验是随机对照试验.

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