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在健康参与者中使用双飞机/单飞机方法进行临床和研究使用的心房维度参考值
A Lupi1, R Angelone1, S Zinato1
1Institute of Radiology, Department of Medicine - DIMED, Padova University Hospital, Padova, Italy.
Clinical radiology
|February 21, 2024
概括
本研究使用心血管磁共振成像来确定右心房和左心房尺寸的参考值. 绝对心房尺寸在性别之间有显著差异,为准确的临床评估推性别特定的参考范围.
科学领域:
- 心血管成像 - 心血管成像
- 心脏解剖学 心脏解剖学
- 医学参考标准 医学参考标准
背景情况:
- 精确测量心房尺寸对于诊断和管理心血管疾病至关重要.
- 现有的参考值可能无法充分考虑人口变化,如性别和年龄.
研究的目的:
- 使用标准的心脏磁共振成像视图来确定左心房和右心房尺寸的参考值.
- 评估这些维度与身体表面积,年龄和性别的相关性.
- 评估单飞机和双飞机方法用于心房评估的可重复性.
主要方法:
- 预计将招募50名年龄在20-70岁之间的健康志愿者 (M:F=1:1).
- 心血管磁共振成像 (CMR) 用于获得两室和四室视图.
- 用单平面和双平面方法测量心房面积和体积,以身体表面积 (BSA) 进行索引,并分析性别和年龄差异.
主要成果:
- 对于心房尺寸测量,在观察者内部和观察者之间具有很好的可重复性 (ICC>0.85).
- 与女性相比,男性的绝对右心房和左心房区域和体积显著更大.
- 按BSA规范化的心房区域没有显著的性别差异,但按BSA指数的右心房体积在男性中仍然明显高.
- 在心房尺寸和年龄之间没有发现显著的相关性.
结论:
- 单飞机方法是评估心房尺寸的快速和可重复的技术.
- 在绝对心房尺寸中存在显著的基于性别的差异.
- 为临床实践,建议为心房尺寸设置性别特定的参考范围.
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