基于对最近的研究进行系统审查的皮肤透性数据的更新
Lisa Chedik1, Shamkhal Baybekov2, Frédéric Cosnier3
1Institut national de recherche et de sécurité pour la prévention des accidents du travail et des maladies professionnelles (INRS), Dept Toxicologie et Biométrologie, 1 rue du Morvan, 54519, Vandoeuvre-lès-Nancy, France. lisa.chedik@inrs.fr.
Scientific data
|February 21, 2024
概括
本综述汇总了2012-2021年皮肤透性数据,创建了SkinPiX数据集. 这一协调资源有助于理解异生菌的皮肤吸收,用于药物开发和风险评估.
科学领域:
- 药理学和毒理学 药理学和毒理学
- 皮肤病学 皮肤病学
- 环境健康 环境健康
背景情况:
- 异生菌的皮肤吸收对于药物/化品开发和化学风险评估至关重要.
- 像HuskinDB这样的现有数据集存在,但由于可变的实验条件而面临挑战.
- 为了可靠的预测建模和风险评估,需要统一的皮肤透性数据.
结论:
- 皮肤PiX代表了皮肤透性数据的重大更新和协调.
- 该数据集有助于监测研究进展,并确定有关化学型.
- 它作为一个有价值的资源,用于推进研究异生菌皮肤吸收和风险评估.
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