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胰岛素和IGF-1对CD4+ T细胞线粒体,新陈代谢和功能都有重叠和独特的影响

Kaitlin Kiernan1, Yazan Alwarawrah2, Amanda G Nichols2

  • 1Department of Immunology, Duke University School of Medicine, Durham, NC, USA.

Scientific reports
|February 21, 2024
PubMed
概括

胰岛素和IGF-1对CD4+T细胞的影响不同. IGF-1 独特地促进了 Th17 细胞的 IL-17 生产和代谢,同时通过线粒体提供细胞保护.

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