UFM1 E3 连接酶促进了 ER 中的 60S 核糖体子单元的回收

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Updated: Jul 2, 2025

Single Molecule Fluorescence Energy Transfer Study of Ribosome Protein Synthesis
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Single Molecule Fluorescence Energy Transfer Study of Ribosome Protein Synthesis

Published on: July 6, 2021

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Paul A DaRosa1, Ivan Penchev2, Samantha C Gumbin1

  • 1Department of Biology, Stanford University, Stanford, CA, USA.

Nature
|February 21, 2024
PubMed
概括

乌比基和类似乌比基的蛋白质 (UBL) 调节细胞的行为. 这项研究揭示了UFM1连接酶如何修改核糖体蛋白L24,帮助从ER膜中拯救和回收60S子单元.

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