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Updated: Jul 2, 2025

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
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通过SIR2效应线组件激活Thoeris抗病毒系统

Giedre Tamulaitiene1, Dziugas Sabonis2, Giedrius Sasnauskas2

  • 1Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania. giedre.tamulaitiene@bti.vu.lt.

Nature
|February 21, 2024
PubMed
概括

细菌使用像Thoeris这样的防御系统对抗菌体 (菌体) 感染. 这项研究揭示了Thoeris效应器ThsA在结合循环ADP核糖信号时如何通过丝组合激活,从而导致NAD+的快速耗尽.

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