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在多参数MRI中进行前列腺外延伸;是否可能进行术前检测?

Muzaffer Ayaz¹, Yıldız Gülseren¹, İbrahim İnan¹

¹Department of Radiology, Medical School of Istanbul Medeniyet University, Kadikoy, Istanbul, Turkey.

Journal of cancer research and therapeutics

|February 22, 2024

概括

1.5T MRI显示敏感度低,但在前列腺癌 (PCa) 中检测前列腺外延伸 (EPE) 的特异性高. 损伤长度 (LL) 和瘤囊接触长度 (TCL) 可能间接帮助检测EPE,并注意到LL的低估.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
医疗成像医学成像

背景情况:

前列腺外延伸 (EPE) 显著影响前列腺癌 (PCa) 的预后.
使用多参数MRI (mpMRI) 精确的术前检测EPE至关重要.
对于mpMRI来检测微观EPE,需要客观的标准.

研究的目的:

评估1.5TMRI在检测PCa中的EPE方面的有效性.
评估损伤长度 (LL) 和瘤囊接触长度 (TCL) 对EPE检测的有用性.

主要方法:

从110名经过激进前列腺切除术的PCa患者手术前的mpMRI的回顾性分析.
两个独立观察员在1.5TMRI上对LL和TCL进行了评估.
放射学发现与组织病理学映射相关.

主要成果:

1.5T MRI显示了低灵敏度 (40.4%) 和高特异性 (84.5-96.6%) 的EPE检测.
在EPE患者中,平均LL和TCL显著更高.
截止值:LL 14.5 毫米,TCL 9.5 毫米. 与细胞病理学相比,放射性LL被低估了.

结论:

1.5T MRI对EPE检测的灵敏度有局限性,但特异性很高.
在EPE评估中,LL和TCL可以间接有益.
在PCa手术的术前计划中,应考虑LL的放射性低估.

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